Read e-book online Biosensors for Health, Environment and Biosecurity PDF

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By P. Serra

ISBN-10: 9533074434

ISBN-13: 9789533074436

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2006, Phypers and Pierce 2006, Lin, Shih and Chau 2007, Spohn et al. 1996, Pohanka and Zboril 2008, Suman et al. 2005, Haccoun et al. 2006, Di et al. 2007). Examples of materials used as mediators include carbon paste, conducting copolymer, nanostructured Si3N4 and silica materials. Other methods of detecting lactate acid include utilizing semiconductors (Lupu et al. 2007) and electro-chemiluminescent materials (Marquette, Degiuli and Blum 2000). A ZnO nanorod array, which was used to immobilize lactate oxidase oxidase (LOx), was selectively grown on the gate area using low temperature hydrothermal decomposition as illustrated in Figure 24.

After incubation with a PBS buffered solution containing c-erbB-2 antibody at a concentration of 1 μg/ml, the device surface was thoroughly rinsed off with deionized water and dried by a nitrogen blower. 25 µg/ml of c-erbB-2 antigen at a constant drain bias voltage of 500 mV. Any slight changes in the ambient of the HEMT affect the surface charges on the AlGaN/GaN. These changes in the surface charge are transduced into a change in the concentration of the 2DEG in the AlGaN/GaN HEMTs, leading to the slight decrease in the conductance for the device after exposure to c-erbB-2 antigen.

By keeping track of the number of electrons passed through the enzyme, the concentration of glucose can be measured. Due to the importance and difficulty of glucose immobilization, numerous studies have been focused on the techniques of immobilization of glucose with carbon nanotubes, ZnO nano-materials, and gold particles (Bloemen et al. 2007, Park, Boo and Chung 2006). ZnO-based nano-materials are especially interesting due to their non-toxic properties, low cost of fabrication and favorable electrostatic interaction between ZnO and the GOx lever.

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Biosensors for Health, Environment and Biosecurity by P. Serra


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