By Qingjun Liu, Associate Professor Ping Wang
Within the twenty first century, we're witnessing the combination of 2 dynamic disciplines - electronics and biology. for this reason bioelectronics and biosensors became of specific curiosity to engineers and researchers operating in similar biomedical parts. Written through well-known specialists the sector, this modern source is the 1st e-book to systematically introduce the concept that, expertise, and improvement of cell-based biosensors. Readers locate information at the most up-to-date cell-based biosensor versions and novel micro-structure biosensor thoughts. Taking an interdisciplinary process, this distinct quantity offers the most recent leading edge purposes of cell-based biosensors in various biomedical fields. The publication additionally explores destiny tendencies of cell-based biosensors, together with built-in chips, nanotechnology and microfluidics. Over a hundred and forty illustrations support make clear key issues in the course of the publication. Scientists, engineers, and brands focused on the improvement, layout, and alertness of biosensors and bioelectronics.
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Additional info for Cell-Based Biosensors: Principles and Applications (Engineering in Medicine & Biology)
22, 2002, pp. 1849–1856. Michael, P. , “The Neurochip: A New Multielectrode Device for Stimulation and Recording from Cultured Neurons,” J. Neurosci. Methods, No. 87, 1999, pp. 45–56. , Sensors in Biomedical Applications: Fundamentals, Technology and Applications, Lancaster, PA: Technomic, 2000. , and S. Martinoia, “Modeling the Neuron-Microtransducer Junction: From Extracellular to Patch Recording,” IEEE Trans. Biomed. , Vol. 40, No. 14, 1993, pp. 35–41. , “Joining Microelectronics and Microionics: Nerve Cells and Brain Tissue on Semiconductor Chips,” Solid State Electronics, No.
3 per square nanometer. Electric charge density in cell lipid bilayer is less than 1 per square nanometer. Glass surface is easier for cell adherence. When the charge density matches with the density on cell membrane, it facilitates cell adherence. Aminosilane is commonly used in modifying the properties of glass surface. Usually glass is chosen for cell culture because its charge property matches with cell membrane after being treated. It was discovered that it could enhance the electric charge density of the chip surface via immobilizing the amino acid group with abundant positive charging, such as laminin.
114. Xu, G. , “Cell-Based Biosensors: Towards the Development of Cellular Monitoring,” Chin. Sci. , Vol. 47, No. 22, 2002, pp. 1849–1856. Michael, P. , “The Neurochip: A New Multielectrode Device for Stimulation and Recording from Cultured Neurons,” J. Neurosci. Methods, No. 87, 1999, pp. 45–56. , Sensors in Biomedical Applications: Fundamentals, Technology and Applications, Lancaster, PA: Technomic, 2000. , and S. Martinoia, “Modeling the Neuron-Microtransducer Junction: From Extracellular to Patch Recording,” IEEE Trans.
Cell-Based Biosensors: Principles and Applications (Engineering in Medicine & Biology) by Qingjun Liu, Associate Professor Ping Wang